Open Access<p>Circulating miRNA Signatures Associated with Insulin Resistance in Adolescents with Obesity</p>
Author(s) -
Haixia Lin,
Emir Tas,
Elisabet Børsheim,
Kelly E. Mercer
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s273908
Subject(s) - insulin resistance , obesity , microrna , body mass index , medicine , metabolic syndrome , childhood obesity , bioinformatics , endocrinology , oncology , biology , genetics , gene , overweight
MicroRNAs (miRNAs) are implicated in metabolic changes accompanying progression of obesity, insulin resistance (IR), and metabolic disorders in children. Identifying circulating miRNAs that uniquely associate with these disorders may be useful in early identification and prevention of obesity-related complications. We aimed to identify circulating miRNA signatures that distinguish adolescents with obesity and IR from those with obesity unaccompanied by IR.