Open Access<p>Sustained Stimulation of β<sub>2</sub>AR Inhibits Insulin Signaling in H9C2 Cardiomyoblast Cells Through the PKA-Dependent Signaling Pathway</p>
Author(s) -
Jinli Pei,
Zhengpan Xiao,
Ziyi Guo,
Yechun Pei,
Wei Sang,
Hao Wu,
Dayong Wang
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s268028
Subject(s) - stimulation , signal transduction , chemistry , medicine , endocrinology , insulin , microbiology and biotechnology , biology , biochemistry
This study aimed to investigate the role of β 2 adrenergic receptor (β 2 AR) in insulin signaling transduction in H9C2 cardiomyoblast cells to understand the formation of the β 2 AR-insulin receptor (IR) protein complex and its role in insulin-induced Glut4 expression.