Open Access<p>The Association Between Femoral Artery Intima-Media Thickness and Serum Glucagon-Like Peptide-1 Levels Among Newly Diagnosed Patients with Type 2 Diabetes Mellitus</p>
Author(s) -
Tuan Dinh Le,
Nga Phi Thi Nguyen,
Son Tien Nguyen,
Hien Thi Thu Nguyen,
Hoa Thanh Thi Tran,
Thi Ho Lan Nguyen,
Cuu Khoa Nguyen,
Giang Nguyen,
Xuan Nguyen,
Bac Duy Nguyen,
Tuan Ngo,
N. Binh,
Thuc Cong Luong
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s264876
Subject(s) - medicine , diabetes mellitus , cardiology , intima media thickness , blood pressure , type 2 diabetes , type 2 diabetes mellitus , femoral artery , microalbuminuria , endocrinology , brachial artery , carotid arteries
Endothelium dysfunction and decrease of incretin effects occur early in type 2 diabetes mellitus and these changes contribute to diabetic cardiovascular complications such as atherosclerosis, thick intima-media, coronary, and peripheral arterial diseases. In patients with diabetes, the femoral artery is a site of a high incidence of injury in peripheral vascular diseases, and atherosclerotic changes may appear earlier in the femoral artery compared to the carotid artery. This study was conducted to determine the prevalence of increased femoral artery intima-media thickness (IMT) and atherosclerotic plaque and their correlation with serum glucagon-like peptide-1 (GLP-1) levels in newly-diagnosed patients with type 2 diabetes mellitus.