Open Access<p>A Review of Research Progress on Glycemic Variability and Gestational Diabetes</p>
Author(s) -
Wenshu Yu,
Na Wu,
Ling Li,
Hong Ouyang,
Meichen Qian,
Haitao Shen
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s261486
Subject(s) - medicine , glycemic , gestational diabetes , preeclampsia , diabetes mellitus , obstetrics , pregnancy , incidence (geometry) , adverse effect , gestation , pediatrics , endocrinology , physics , biology , optics , genetics
Gestational diabetes mellitus (GDM) is associated with many adverse obstetric outcomes and neonatal outcomes, including preeclampsia, Cesarean section, and macrosomia. Active screening and early diabetes control can reduce the occurrence of adverse outcomes. Glycosylated hemoglobin (HbA1c) only reflects average blood glucose levels, but not glycemic variability (GV). Studies have shown that GV can cause a series of adverse reactions, and good control of GV can reduce the incidence of adverse pregnancy outcomes in patients with GDM. In order to provide clinicians with a better basis for diagnosis and treatment, this study reviewed the measurement, evaluation, and control of GV, the importance of GV for patients with GDM, and correlations between GV and maternal and neonatal outcomes.