Open Access<p>Cyclophilin A (CyPA) as a Novel Biomarker for Early Detection of Diabetic Nephropathy in an Animal Model</p>
Author(s) -
Abdallah Mahmoud El-Ebidi,
Tahia H. Saleem,
Mohamed Saadi,
Hala Abdallah Mahmoud,
Zeinab Mohamed,
Hoda S Sherkawy
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s260293
Subject(s) - cypa , cyclophilin a , diabetic nephropathy , biomarker , cyclophilin , medicine , animal model , cancer research , diabetes mellitus , chemistry , biology , endocrinology , microbiology and biotechnology , biochemistry , gene
Type 2 diabetes mellitus (DM) is the most common single cause of the end-stage renal disease (ESRD). Cyclophilin A (CyPA) is an 18-kD protein. The connection between diabetic nephropathy (DN) and the secreted form of CyPA (sCyPA) has been elucidated in this study that aims to investigate sCyPA correlation with renal dysfunction.