Open Access<p>Dapagliflozin Activates Neurons in the Central Nervous System and Regulates Cardiovascular Activity by Inhibiting SGLT-2 in Mice</p>
Author(s) -
Thiquynhnga Nguyen,
Song Wen,
Min Gong,
Xinlu Yuan,
Dongxiang Xu,
Chaoxun Wang,
Jianlan Jin,
Ligang Zhou
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s258593
Subject(s) - dapagliflozin , blood pressure , c fos , medicine , endocrinology , glycemic , pharmacology , diabetes mellitus , chemistry , type 2 diabetes , biochemistry , gene expression , gene
This study investigates the possible effect and central mechanism of novel antidiabetic medication sodium glucose transporter-2 (SGLT-2i) on the cardiovascular activity.