
<p>The Therapeutic Role of Carotenoids in Diabetic Retinopathy: A Systematic Review</p>
Author(s) -
Mohammad Fathalipour,
Hadis Fathalipour,
Omid Safa,
Peyman Nowrouzi-Sohrabi,
Hossein Mirkhani,
Soheil Hassanipour
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s255783
Subject(s) - carotenoid , medicine , medline , web of science , diabetic retinopathy , checklist , clinical trial , scopus , systematic review , bioinformatics , meta analysis , traditional medicine , pharmacology , diabetes mellitus , psychology , endocrinology , biology , food science , biochemistry , cognitive psychology
Carotenoids are a large group of natural pigments that occur in many foods, fruits, and vegetables. Several studies have shown a number of biological properties of carotenoids, particularly beneficial impacts on cancer, metabolic, neurodegenerative, and cardiovascular diseases. However, recent evidence has shown that these compounds could prevent, delay, and ameliorate diabetic retinopathy (DR). The aim of current study was to review the therapeutic effects of carotenoids in the treatment of DR and discuss the molecular mechanisms that are behind these pharmacological activities.