Open Access<p>Salivary Amylase Gene Copy Number Is Associated with the Obesity and Inflammatory Markers in Children</p>
Author(s) -
Vaithinathan Selvaraju,
Chandra Mohan Kurapaty Venkatapoorna,
Jeganathan Ramesh Babu,
Thangiah Geetha
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s251359
Subject(s) - saliva , resistin , medicine , obesity , overweight , endocrinology , insulin resistance , adiponectin
We have recently shown that the copy number of salivary amylase ( AMY1 ) gene was significantly decreased, and the obesity-related salivary biomarkers resistin, MCP-1, TNF-α, IL-6, and CRP were signicantly increased in overweight/obese children compared to normal weight. This study aimed to evaluate the association of AMY1 copy number variant (CNV) with obesity and inflammatory markers. Seventy-six participants aged between 6 and 10 years have participated, and the saliva samples were collected along with the anthropometric measurements.