Open Access<p>Advances with Long Non-Coding RNAs in Diabetic Peripheral Neuropathy</p>
Author(s) -
Men Wu,
Yonghao Feng,
Xin Shi
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s249232
Subject(s) - peripheral neuropathy , epigenetics , diabetes mellitus , long non coding rna , diabetic neuropathy , bioinformatics , medicine , neuropathic pain , gene , malat1 , gene expression , microrna , non coding rna , rna , biology , genetics , endocrinology , neuroscience
Long non-coding RNAs (lncRNAs) are a group of non-coding RNAs longer than 200 nucleotides, which are defined as transcripts. The lncRNAs are involved in regulating gene expression at epigenetic, transcriptional, and post-transcriptional levels. Recent studies have found that lncRNA is closely related to many diseases like neurological diseases, endocrine and metabolic disorders. Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus. In this review, we highlight the latest research related to lncRNAs in DPN.