Open Access<p>Low Vitamin D Serum Level Is Associated with HDL-C Dyslipidemia and Increased Serum Thrombomodulin Levels of Insulin-Resistant Individuals</p>
Author(s) -
Fatemeh Saheb SharifAskari,
Narjes Saheb Sharif-Askari,
Rabih Halwani,
Salah Abusnana,
Rifat Hamoudi,
Nabil Sulaiman
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s245742
Subject(s) - dyslipidemia , medicine , endocrinology , insulin resistance , lipid profile , vitamin d and neurology , insulin , lipoprotein , diabetes mellitus , cholesterol
Insulin-resistant individuals are known to have dyslipidemia and are predicted to be at high risk of cardiovascular events. Vitamin D deficiency was shown to be associated with dyslipidemia; however, the type of dyslipidemia associated with vitamin D deficiency in insulin-resistant individuals is not determined. Furthermore, there is evidence linking insulin resistance with low-grade inflammation suggesting levels of pro-inflammatory cytokines to be increased in insulin-resistant states.