Open Access<p>Characteristics of Gastric Microbiota in GK Rats with Spontaneous Diabetes: A Comparative Study</p>
Author(s) -
Xin Kang,
Lijun Zhan,
Xiaoguang Lu,
Jianbo Song,
Yilong Zhong,
Yi Wang,
Yahui Yang,
Zhining Fan,
Xiao Zheng Jiang,
Ruru Sun
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s242698
Subject(s) - firmicutes , lachnospiraceae , biology , gut flora , proteobacteria , lactobacillus , veillonella , medicine , endocrinology , bacteria , immunology , 16s ribosomal rna , streptococcus , genetics
The Goto-Kakizaki (GK) rat, developed from repeated inbreeding of glucose-intolerant Wistar rats, has been widely used to explore the development of spontaneous type-2 diabetes mellitus (T2DM). However, the gastric microbiota of GK and Wistar rats are still unclear. This study aimed to understand the gastric microbiota characteristics of GK rats by comparing it with non-diabetic Wistar rats.