Open Access<p>mRNAs expression profiles of high glucose-induced memory in human umbilical vein endothelial cells</p>
Author(s) -
Guoxi Jin,
Qiong Wang,
Xiuying Pei,
Xiaoli Li,
Xiaolei Hu,
Erqin Xu,
Minglong Li
Publication year - 2019
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s206270
Subject(s) - kegg , umbilical vein , transcriptome , biology , gene , microbiology and biotechnology , gene expression , signal transduction , phosphorylation , cell cycle , fold change , genetics , in vitro
A long-term "memory" of hyperglycemic stress, even when glycemia is normalized, has been previously reported in endothelial cells. However, the molecular mechanism of "metabolic memory" (MM) remains unknown. In this report, we sought to screen at the whole transcriptome level the genes that participate in MM.