Open AccessSorafenib Attenuates Fibrotic Hepatic Injury Through Mediating Lysine Crotonylation
Author(s) -
Xiaofeng Chen,
Shaoxiu Ji
Publication year - 2022
Publication title -
drug design, development and therapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s368306
Subject(s) - sorafenib , fibrosis , ccl4 , hepatocellular carcinoma , alanine transaminase , hepatic fibrosis , carbon tetrachloride , chemistry , immunohistochemistry , medicine , endocrinology , organic chemistry
Liver fibrosis is an independent contributor of chronic liver diseases, and regressing liver fibrosis is considered a potential therapeutic target for chronic liver diseases. We aimed to explore the effects and mechanism of sorafenib in liver fibrosis.