Open AccessNetwork Pharmacology-Based Strategy Combined with Molecular Docking and in vitro Validation Study to Explore the Underlying Mechanism of Huo Luo Xiao Ling Dan in Treating Atherosclerosis
Author(s) -
Tao Sun,
Wenjuan Quan,
Sha Peng,
Dongmei Yang,
Jiaqin Liu,
Chaoping He,
Yu Chen,
Bo Hu,
Qinhui Tuo
Publication year - 2022
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s357483
Subject(s) - docking (animal) , luteolin , chemistry , in vitro , mapk/erk pathway , computational biology , signal transduction , pharmacology , biochemistry , biology , quercetin , antioxidant , medicine , nursing
Huo Luo Xiao Ling Dan (HLXLD), a famous Traditional Chinese Medicine (TCM) classical formula, possesses anti-atherosclerosis (AS) activity. However, the underlying molecular mechanisms remain obscure.