Open AccessA Dose-Response Relationship Study of Prophylactic Nalbuphine to Reduce Pain During the Awakening Period in Patients Undergoing Laparoscopic Total Hysterectomy: A Randomized, Controlled, Double-Blind Clinical Study
Author(s) -
Min Wang,
Dongyue Wang,
Jingzhi Zuo,
Tianyu Li,
Zheng Niu,
JianWei Xie,
Dashi Qi
Publication year - 2022
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s356582
Subject(s) - nalbuphine , medicine , anesthesia , adverse effect , saline , hysterectomy , confidence interval , randomized controlled trial , surgery , opioid , receptor
Prophylactic intravenous nalbuphine was administered to observe its median effective dose (ED 50 ) in reducing pain after undergoing laparoscopic total hysterectomy. To investigate the effect of different doses of nalbuphine on postoperative analgesia and adverse reactions in patients.