Open AccessProtective Effects of Mogroside V on Oxidative Stress Induced by H2O2 in Skin Fibroblasts
Author(s) -
Qiuting Mo,
Hao Fu,
Dan Zhao,
Jiachan Zhang,
Changtao Wang,
Dongdong Wang,
Meng Li
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s337524
Subject(s) - oxidative stress , superoxide dismutase , catalase , antioxidant , malondialdehyde , glutathione peroxidase , reactive oxygen species , chemistry , glutathione , hydrogen peroxide , pharmacology , biochemistry , skin aging , enzyme , biology , medicine , dermatology
Damage caused by oxidative stress leads to the premature aging of cells. Mogrosides, the main active components of Siraitia grosvenorii , have strong antioxidant activity; however, it is unclear whether mogroside V (MV) exerts these effects in skin cells. This was investigated in the present study by evaluating the protective effects of MV against oxidative damage induced by hydrogen peroxide (H 2 O 2 ) in skin fibroblasts.