Open AccessIntegrated Network Pharmacology and Metabolomics Analysis to Reveal the Potential Mechanism of Siwu Paste on Aplastic Anemia Induced by Chemotherapy Drugs
Author(s) -
Dan He,
Dan Wan,
Qing Du,
Bingbing Shen,
Lin Chen,
Liang-Zi Fang,
Jian-jun Kuang,
Chunyu Tang,
Ping Cai,
Rong Yu,
Shuihan Zhang,
Jianhua Huang
Publication year - 2022
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
ISSN - 1177-8881
DOI - 10.2147/dddt.s327433
Subject(s) - metabolomics , adme , pharmacology , sphingolipid , kegg , metabolic pathway , signal transduction , biology , chemistry , computational biology , biochemistry , metabolism , bioinformatics , drug , transcriptome , gene expression , gene
This study aimed to reveal the multicomponent synergy mechanisms of SWP based on network pharmacology and metabolomics for exploring the relationships of active ingredients, biological targets, and crucial metabolic pathways.