Open AccessTranscriptome-Based Analysis Reveals Therapeutic Effects of Resveratrol on Endometriosis in aRat Model
Author(s) -
Chunyan Wang,
Zhengyun Chen,
Xianlei Zhao,
Cuicui Lin,
Shenghui Hong,
Yuhan Lou,
Xiaomeng Shi,
Miaomiao Zhao,
Xiaohang Yang,
MinXin Guan,
Yongmei Xi
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
ISSN - 1177-8881
DOI - 10.2147/dddt.s323790
Subject(s) - resveratrol , endometriosis , lesion , medicine , immunohistochemistry , macrophage polarization , pelvic pain , endometrium , inflammation , pharmacology , endocrinology , macrophage , pathology , biology , surgery , in vitro , biochemistry
Endometriosis (EMs) is associated with severe chronic pelvic pain and infertility and the development of improved EMs treatment options is an ongoing focus. In this study, we investigated the effects of resveratrol on EMs and analyzed transcriptional changes in the lesions of model rats before and after resveratrol treatment.