Open AccessAdjuvant Sufentanil Decreased the EC50 of Epidural Ropivacaine for Labor Analgesia in Healthy Term Pregnancy
Author(s) -
Bo Xiang,
Jian Yang,
Xiaofeng Lei,
Jiang Yu
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s307478
Subject(s) - ropivacaine , sufentanil , medicine , anesthesia , sedation , apgar score , hemodynamics , labor pain , pregnancy , birth weight , biology , genetics
The optimal concentration of ropivacaine as epidural labor analgesia combined with sufentanil has not been established. This study aimed to determine the median effective concentration (EC50) of epidural ropivacaine for labor analgesia in healthy term pregnancy when co-administered with sufentanil as an adjuvant or alone.