Open AccessProtective Effects of Silymarin Against D-Gal/LPS-Induced Organ Damage and Inflammation in Mice
Author(s) -
Xin Zhao,
Haoxiang Wang,
Yue Yang,
Yuting Gou,
Zhiying Wang,
Dan Yang,
Chong Li
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s305033
Subject(s) - inflammation , pharmacology , glutathione , kidney , lipopolysaccharide , chemistry , antioxidant , endocrinology , medicine , biochemistry , enzyme
Silymarin contains various flavonoids and exhibits antioxidative, anti-inflammatory, and anticancer effects, in addition to other pharmacological properties. This study explored the alleviating effect of silymarin on multiple-organ damage induced by D-galactose/lipopolysaccharide in Kunming mice.