Open AccessPharmacokinetics of Linezolid Dose Adjustment for Creatinine Clearance in Critically Ill Patients: A Multicenter, Prospective, Open-Label, Observational Study
Author(s) -
Xipei Wang,
Yifan Wang,
Fen Yao,
Shenglong Chen,
Yating Hou,
Zhijie Zheng,
Jingqin Luo,
Binghui Qiu,
Zhanfu Li,
Yirong Wang,
Zheng Wu,
Jinhua Lan,
Chunbo Chen
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s303497
Subject(s) - medicine , renal function , dosing , pharmacokinetics , volume of distribution , urology , population , creatinine , regimen , pharmacodynamics , environmental health
The aim of this study is to use a population pharmacokinetic (PK) approach to evaluate the optimal dosing strategy for linezolid (LNZ) in critically ill patients.