Open AccessStudy on Hepatotoxicity of Rhubarb Based on Metabolomics and Network Pharmacology
Author(s) -
Shanze Li,
Yuming Wang,
Chunyan Li,
Na Yang,
Hongxin Yu,
Wenjie Zhou,
Siyu Chen,
Shenshen Yang,
Yubo Li
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s301417
Subject(s) - metabolomics , pharmacology , traditional medicine , medicine , biology , bioinformatics
Rhubarb, as a traditional Chinese medicine, is the preferred drug for the treatment of stagnation and constipation in clinical practice. It has been reported that rhubarb possesses hepatotoxicity, but its mechanism in vivo is still unclear.