Open AccessExosomal Circ-XIAP Promotes Docetaxel Resistance in Prostate Cancer by Regulating miR-1182/TPD52 Axis
Author(s) -
Hui Zhang,
Minghui Li,
Jing Zhang,
Yanbing Shen,
Qi Gui
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s300376
Subject(s) - xiap , gene knockdown , inhibitor of apoptosis , cancer research , apoptosis , chemistry , cell cycle , cell growth , microbiology and biotechnology , biology , programmed cell death , caspase , biochemistry
Exosomal circular RNAs (circRNAs) are involved in the pathogenesis of prostate cancer (PCa) and chemotherapy resistance. This research aimed to explore the function and molecular mechanism of circRNA X-linked inhibitor of apoptosis (circ-XIAP) in docetaxel (DTX) resistance of PCa.