Open AccessTemozolomide-Induced Changes in Gut Microbial Composition in a Mouse Model of Brain Glioma
Author(s) -
Xiaochong Li,
BangSheng Wu,
Yi Jiang,
Jie Li,
Xinghuan Wang,
Ma C,
Yirong Li,
Jie Yao,
Xiaoqing Jin,
Zhiqiang Li
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s298261
Subject(s) - temozolomide , glioma , akkermansia , gut flora , biology , bifidobacterium , bacteroidetes , firmicutes , lactobacillus , akkermansia muciniphila , microbiome , microbiology and biotechnology , cancer research , immunology , bioinformatics , bacteria , 16s ribosomal rna , genetics
Gut microbiota is associated with the progression of brain tumors. However, the alterations in gut microbiota observed during glioma growth and temozolomide (TMZ) therapy remain poorly understood.