Open AccessTetramethylpyrazine Improves Cognitive Function of Alzheimer’s Disease Mice by Regulating SSTR4 Ubiquitination
Author(s) -
Guohu Weng,
Bo Zhou,
Tao Liu,
Zhengxin Huang,
Shixiong Huang
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
ISSN - 1177-8881
DOI - 10.2147/dddt.s290030
Subject(s) - downregulation and upregulation , tetramethylpyrazine , mg132 , apoptosis , gene silencing , viability assay , ubiquitin , chemistry , autophagy , ubiquitin ligase , proteasome inhibitor , microbiology and biotechnology , biology , cancer research , medicine , biochemistry , pathology , gene , alternative medicine
Many researches have investigated the functions of tetramethylpyrazine (TMP) in Alzheimer's disease (AD). This study aimed to discuss the underlying mechanism of TMP in AD mice.