Open AccessEpigallocatechin-3-Gallate Provides Protection Against Alzheimer’s Disease-Induced Learning and Memory Impairments in Rats
Author(s) -
Shanji Nan,
Peng Wang,
Yizhi Zhang,
Jia Fan
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s289473
Subject(s) - morris water navigation task , western blot , acetylcholinesterase , neuroprotection , hippocampus , pharmacology , reverse transcription polymerase chain reaction , epigallocatechin gallate , chemistry , hyperphosphorylation , microbiology and biotechnology , medicine , antioxidant , biochemistry , biology , phosphorylation , enzyme , gene expression , polyphenol , gene
Recent evidence has highlighted the anti-inflammatory properties of the constituent of Green Tea Polyphenols (GTP), epigallocatechin-3-gallate (EGCG) which has been suggested to exert a neuroprotective effect on Alzheimer's disease (AD). The current study aimed to elucidate the effect of EGCG on memory function in rats with AD.