Open AccessThe Antimicrobial Peptide Melectin Shows Both Antimicrobial and Antitumor Activity via Membrane Interference and DNA Binding
Author(s) -
Xiaolei Liang,
Jiexi Yan,
YingWei Lu,
Shan Liu,
Xiaojing Chai
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
ISSN - 1177-8881
DOI - 10.2147/dddt.s288219
Subject(s) - antimicrobial peptides , antimicrobial , peptide , mechanism of action , cytotoxicity , venom , biology , multiple drug resistance , dna , chemistry , biochemistry , antibiotics , computational biology , microbiology and biotechnology , in vitro
Increasingly complex diseases require novel drugs for their treatment. Antimicrobial peptides (AMPs) are promising candidate treatments due to their broad existence and special characteristics. However, the current understanding of AMPs is not sufficient to allow them to be produced commercially for clinical use.