Open AccessGypenosides Inhibit Inflammatory Response and Apoptosis of Endothelial and Epithelial Cells in LPS-Induced ALI: A Study Based on Bioinformatic Analysis and in vivo/vitro Experiments
Author(s) -
Qing Tu,
Yabing Zhu,
Yuan Yuan,
Long Guo,
Lu Liu,
Liangfang Yao,
Yun Zou,
Jinbao Li,
Feng Chen
Publication year - 2021
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s286297
Subject(s) - kegg , in vivo , apoptosis , inflammation , tumor necrosis factor alpha , in vitro , biology , medicine , cancer research , immunology , gene expression , gene , transcriptome , biochemistry , genetics
Severe inflammatory response leads to poor prognosis of acute lung injury (ALI), the role of gypenosides (GPs) on ALI is not fully clear. The study aimed at investigating the effects of GPs on ALI.