Open Access<p>Research on the Potential Mechanism of Gentiopicroside Against Gastric Cancer Based on Network Pharmacology</p>
Author(s) -
Yanxia Huang,
Jiatong Lin,
Wu Yi,
Qinghua Liu,
Lixue Cao,
Yongcong Yan,
Anqi Fu,
Tao Huang,
Yingcheng Lyu,
Qihui Huang,
Jie Wang
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
ISSN - 1177-8881
DOI - 10.2147/dddt.s270757
Subject(s) - kegg , gene ontology , computational biology , mechanism (biology) , interaction network , mechanism of action , cancer , systems pharmacology , biology , pharmacology , gene , bioinformatics , traditional medicine , medicine , gene expression , biochemistry , in vitro , genetics , drug , philosophy , epistemology
Gastric cancer was still one of the commonly diagnosed cancer types and the third-most common cause of cancer-related death in the world. Gentiopicroside, which is extracted from the Gentianella acuta , is commonly used in both traditional treatment and modern clinical care; therefore, its anticancer effects have been attracted more attention. However, the systematic analysis of action mechanism of Gentiopicroside on gastric cancer (GC) has not yet been carried out.