Open Access<p>Simvastatin-Nicotinamide Co-Crystals: Formation, Pharmaceutical Characterization and in vivo Profile</p>
Author(s) -
Fahad Mehmood Khan,
Mahmood Ahmad,
Hafiz Arfat Idrees
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s270742
Subject(s) - simvastatin , nicotinamide , in vivo , pharmacology , chemistry , characterization (materials science) , medicine , materials science , nanotechnology , biochemistry , biology , microbiology and biotechnology , enzyme
To enhance the solubility and dissolution profile of simvastatin (SIM) through co-crystallization with varying ratios of nicotinamide (NIC) using various co-methods.