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The protective effects of epigallocatechin gallate (EGCG) on interleukin-1β (IL-1β)-induced apoptosis were investigated in murine MIN 6 pancreatic β-cells. The role of uncoupling protein-3 (UCP 3 ) signaling in this process was also explored.

drug design development and therapy

&lt;p&gt;EGCG Upregulates UCP&lt;sub&gt;3&lt;/sub&gt; Levels to Protect MIN&lt;sub&gt;6&lt;/sub&gt; Pancreatic Islet Cells from Interleukin-1β-Induced Apoptosis&lt;/p&gt;