Open Access<p>Pseudolaric Acid B Inhibits Proliferation, Invasion, and Angiogenesis in Esophageal Squamous Cell Carcinoma Through Regulating CD147</p>
Author(s) -
Zhe Yin,
Huarong Cai,
Zhiqiang Wang,
Yuzhu Jiang
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s269915
Subject(s) - angiogenesis , in vivo , cancer research , cell growth , cell migration , mmp2 , apoptosis , in vitro , cell culture , cell , biology , cancer , metastasis , biochemistry , genetics , microbiology and biotechnology
Esophageal squamous cell carcinoma (ESCC) is a common malignant tumor of the digestive system. Studies have shown that pseudolaric acid B (PAB) has several pharmacological effects like anti-microtubule, anti-angiogenesis, and antitumor functions, while the effect and mechanism of PAB on esophageal cancer are still unclear. This study was designed to investigate the effects of PAB on ESCC.