Open Access<p>Curcumin Protects Against Radiotherapy-Induced Oxidative Injury to the Skin</p>
Author(s) -
Dheyauldeen Shabeeb,
Ahmed Eleojo Musa,
Hayder Shabeeb Abd Ali,
Masoud Najafi
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s265228
Subject(s) - curcumin , superoxide dismutase , glutathione peroxidase , pharmacology , malondialdehyde , catalase , oxidative stress , glutathione , radiation therapy , chemistry , antioxidant , medicine , biochemistry , enzyme
Side-effects to normal tissues reduce the therapeutic window of radiotherapy. During radiotherapy, the skin is inevitably exposed to doses of ionizing radiation, leading to varying degrees of skin damage. Natural antioxidants have been explored for their radioprotective potentials. Thus, the present study aimed to investigate the protective effect of curcumin against radiotherapy-induced oxidative damage to the skin.