Open Access<p>Development, Characterization, and in-vivo Pharmacokinetic Study of Lamotrigine Solid Self-Nanoemulsifying Drug Delivery System</p>
Author(s) -
Rehab Abdelmonem,
Marian Sobhy Azer,
Amna M. A. Makky,
Abdel-Azim Zaghloul,
Mohamed A. El-Nabarawi,
Aly Nada
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s263898
Subject(s) - differential scanning calorimetry , chromatography , bioavailability , chemistry , dissolution , factorial experiment , drug delivery , scanning electron microscope , nuclear chemistry , pharmacokinetics , pulmonary surfactant , materials science , pharmacology , organic chemistry , medicine , mathematics , biochemistry , physics , statistics , composite material , thermodynamics
This study aimed to prepare solid self-nanoemulsified drug delivery system (S-SNEDDS) of lamotrigine (LMG) for enhancing its dissolution and oral bioavailability (BA).