Open Access<p>Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis</p>
Author(s) -
Zhi Li,
Jidong Cheng,
Jiuxiang Liu
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s255823
Subject(s) - baicalin , autophagy , apoptosis , annexin , chondrocyte , blot , chemistry , viability assay , microbiology and biotechnology , cartilage , biology , biochemistry , in vitro , anatomy , gene , high performance liquid chromatography , chromatography
Osteoarthritis (OA) is one of the most prevalent and degenerative diseases with complicated pathology including articular cartilage degradation, subchondral sclerosis and synovitis. Chondrocytes play a crucial role in maintaining cartilage integrity.