Open Access<p>Sugar Codes Conjugated Alginate: An Innovative Platform to Make a Strategic Breakthrough in Simultaneous Prophylaxis of GERD and <em>Helicobacter pylori</em> Infection</p>
Author(s) -
Saeed Moayedi,
Abbas Yadegar,
Saeed Balalaie,
M E Yarmohammadi,
Mohammad Reza Zali,
Hideji Suzuki,
Gert Fricker,
Ismaeil Haririan
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s255611
Subject(s) - gerd , helicobacter pylori , sugar , conjugated system , in vitro , helicobacter pylori infection , reflux , in vivo , gastroenterology , disease , chemistry , medicine , biology , biochemistry , microbiology and biotechnology , organic chemistry , polymer
Currently, gastroesophageal reflux disease (GERD) is one of the most ubiquitous problems in clinical practice. An antacid-alginate combination (under the trade name Gaviscon) is a natural-based product that effectively suppresses GERD. This product acts via the formation of viscous gel that floats on the top of the gastric content. On the other hand, efficient management of Helicobacter pylori infection with minimal side effects is an important goal for gastroenterologists. Furthermore, some H. pylori -positive patients suffer from GERD.