Open Access<p>Network Pharmacology-Based Prediction and Verification of the Active Ingredients and Potential Targets of Zuojinwan for Treating Colorectal Cancer</p>
Author(s) -
Siqi Huang,
Zheyu Zhang,
Wenqun Li,
Fanyun Kong,
Pan Yi,
Jianhua Huang,
Dan Mao,
Weijun Peng,
Sifang Zhang
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s250991
Subject(s) - wogonin , kegg , akt1 , baicalein , computational biology , pi3k/akt/mtor pathway , pharmacology , chemistry , signal transduction , biology , scutellaria baicalensis , gene ontology , biochemistry , gene , medicine , traditional chinese medicine , gene expression , alternative medicine , pathology
Zuojinwan (ZJW), a famous Chinese medicine formula, has been widely used to treat colorectal cancer (CRC). However, its bioactive compounds, potential targets, and molecular mechanism remain largely elusive.