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The aim of the present study was to investigate the interactions of the main components of Lygodium root (ie, p-coumaric acid, acacetin, apigenin, buddleoside and Diosmetin-7-O-β-D-glucopyranoside) with cytochrome P450 3A enzyme activity both in vitro and in vivo.

<p>Inhibitory Effect of <em>Lygodium</em> Root on the Cytochrome P450 3A Enzyme in vitro and in vivo</p>