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Drug-induced liver injury (DILI) is the most common cause of acute liver failure. The aim of this study was to investigate the molecular mechanisms by which Ganoderma lucidum mushroom (GLM) may ameliorate cisplatin (CP)-induced hepatotoxicity theoretically and experimentally.

drug design development and therapy

&lt;p&gt;Suppression of Cisplatin-Induced Hepatic Injury in Rats Through Alarmin High-Mobility Group Box-1 Pathway by &lt;em&gt;Ganoderma lucidum&lt;/em&gt;: Theoretical and Experimental Study&lt;/p&gt;