Open Access<p>Nimodipine Improves Cognitive Impairment After Subarachnoid Hemorrhage in Rats Through IncRNA NEAT1/miR-27a/MAPT Axis</p>
Author(s) -
Junwei Li,
Shaohua Ren,
Jinrui Ren,
Zigang Zhen,
Lirong Li,
Xudong Hao,
Hongming Ji
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s248115
Subject(s) - nimodipine , subarachnoid hemorrhage , western blot , medicine , apoptosis , pharmacology , anesthesia , biology , biochemistry , gene , calcium
Subarachnoid hemorrhage (SAH) is a cerebral hemorrhage disease that severely damages the brain and causes cognitive impairment (CI). Therefore, accurate and appropriate treatment strategies are urgently needed. The application of nimodipine can not only improve blood circulation in patients with SAH but also repair ischemic neuron injury.