Open Access<p>The Regulating Mechanism of Chrysophanol on Protein Level of CaM-CaMKIV to Protect PC12 Cells Against Aβ<sub>25-35</sub>-Induced Damage</p>
Author(s) -
Ting Ye,
Hua-Wu Gao,
Wei-Ting Xuan,
Shu Ye,
Peng Zhou,
Xinquan Li,
Yan Wang,
Hang Song,
Yanyan Liu
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s245128
Subject(s) - western blot , microbiology and biotechnology , calmodulin , protein kinase a , apoptosis , neuroprotection , viability assay , kinase , tau protein , chemistry , biology , pharmacology , biochemistry , medicine , gene , enzyme , disease , alzheimer's disease
To investigate the neuroprotective effect of chrysophanol (CHR) on PC12 treated with Aβ 25-35 , and the involved mechanism.