Open Access<p>Salidroside Alleviates Cartilage Degeneration Through NF-κB Pathway in Osteoarthritis Rats</p>
Author(s) -
Hui Gao,
Peng Lü,
Chao Li,
Qinlong Ji,
Ping Li
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s242862
Subject(s) - salidroside , osteoarthritis , inflammation , chemistry , aggrecan , pharmacology , apoptosis , cartilage , medicine , nf κb , endocrinology , immunology , pathology , biochemistry , articular cartilage , anatomy , alternative medicine
Osteoarthritis (OA) is the most common disease, which seriously affects the daily life of the elderly. Currently, no traditional or drug therapy has been shown to explicitly block the progression of OA. Salidroside (Sal) is a bioactive component of Rhodiola rosea , which has many beneficial effects on human health. However, the role and mechanism of Sal in OA have not been reported.