Open Access<p>Targeted Therapy for Hepatocellular Carcinoma: Co-Delivery of Sorafenib and Curcumin Using Lactosylated pH-Responsive Nanoparticles</p>
Author(s) -
Yun Bian,
Dong Guo
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s238955
Subject(s) - sorafenib , curcumin , hepatocellular carcinoma , chemistry , zeta potential , liver cancer , nanoparticle , cancer research , pharmacology , nanotechnology , biochemistry , medicine , materials science
Hepatocellular carcinoma (HCC) is a leading cancer worldwide. In the present investigation, sorafenib (SFN) and curcumin (CCM) were co-delivered using pH-sensitive lactosylated nanoparticles (LAC-NPs) for targeted HCC treatment.