Open Access<p>Anti-Breast Cancer Effect of 2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione in vivo and in vitro Through MAPK Signaling Pathway</p>
Author(s) -
Xing Zhou,
Xingchun Wu,
Luhui Qin,
Sisi Lu,
Hongliang Zhang,
Jinbin Wei,
Lixiu Chen,
Liping Jiang,
Yani Wu,
Chunxia Chen,
Renbin Huang
Publication year - 2020
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s237699
Subject(s) - microbiology and biotechnology , apoptosis , cell cycle , biology , western blot , flow cytometry , chemistry , cancer research , biochemistry , gene
2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione (DMDD) has been reported to inhibit a variety of cancer cell lines. The purpose of this study was to investigate the effects of DMDD on 4T1 breast cancer cells and the effects of DMDD on 4T1 breast cancer in mice and its molecular mechanisms.