Open Access<p>Pharmacokinetic interactions between telmisartan/amlodipine and rosuvastatin after multiple oral administrations in healthy Korean male subjects</p>
Author(s) -
Seol Ju Moon,
JiYoung Jeon,
Kyungho Jang,
KyungSang Yu,
Yeji Lim,
MinGul Kim
Publication year - 2019
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s210364
Subject(s) - cmax , rosuvastatin , pharmacokinetics , medicine , telmisartan , rosuvastatin calcium , amlodipine , cohort , pharmacology , confidence interval , crossover study , urology , placebo , blood pressure , alternative medicine , pathology
Hypertension and dyslipidemia are major risk factors for cardiovascular diseases, and reduction of cardiovascular risks can be achieved by combining antihypertensive therapy with statins. The objective of this study was to evaluate the pharmacokinetic interaction between telmisartan/amlodipine fixed dose combination and rosuvastatin in healthy Korean male volunteers.