Open Access<p>Efficacy and safety of tacrolimus vs cyclophosphamide in the therapy of patients with idiopathic membranous nephropathy: a meta-analysis</p>
Author(s) -
Wenshan Lin,
Hongyan Li,
Shujun Lin,
Tian-Biao Zhou
Publication year - 2019
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s209211
Subject(s) - medicine , tolerability , cochrane library , meta analysis , cyclophosphamide , randomized controlled trial , adverse effect , tacrolimus , gastroenterology , chemotherapy , transplantation
As one of the therapeutic drugs for idiopathic membranous nephropathy (IMN), tacrolimus (TAC) has not been fully vindicated for its efficacy and tolerability. A meta-analysis was performed to detect the efficacy and safety of TAC plus glucocorticoid vs cyclophosphamide (CTX) plus glucocorticoid in therapy of patients with IMN.