Open Access<p>Hexyl alginate derivative, an amphiphilic innovative buccal film-forming material of promising mechanical and release characteristics for the improvement of repaglinide bioavailability</p>
Author(s) -
Ahmed Khames
Publication year - 2019
Publication title -
drug design, development and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.964
H-Index - 64
ISSN - 1177-8881
DOI - 10.2147/dddt.s196425
Subject(s) - bioavailability , ultimate tensile strength , repaglinide , materials science , chemistry , plasticizer , box–behnken design , buccal administration , nuclear chemistry , chromatography , biomedical engineering , response surface methodology , pharmacology , composite material , insulin , medicine , metformin , endocrinology
Association of long hydrocarbon chain with alginate molecule imparts surface active properties and increases chain flexibility.