Open Access<p>Metabolism and Excretion of Intravenous, Radio-Labeled Amisulpride in Healthy, Adult Volunteers</p>
Author(s) -
Gabriel Fox,
Ad F. Roffel,
Jan Hartstra,
Linda A Bussian,
Sjoerd P. van Marle
Publication year - 2019
Publication title -
clinical pharmacology
Language(s) - English
Resource type - Journals
ISSN - 1179-1438
DOI - 10.2147/cpaa.s234256
Subject(s) - amisulpride , urine , excretion , chemistry , feces , dosing , pharmacokinetics , pharmacology , medicine , endocrinology , antipsychotic , biology , paleontology , schizophrenia (object oriented programming) , psychiatry
Intravenous amisulpride, a dopamine D 2 /D 3 antagonist, has recently been shown in trials to be an effective antiemetic at low doses. This study was conducted to investigate the metabolism and elimination of a single dose of intravenous 14 C-labeled amisulpride in healthy, adult volunteers.