Open Access<p>A Single- and Multiple-Dose Study to Evaluate the Pharmacokinetics of Fixed-Dose Grazoprevir/Elbasvir in Healthy Chinese Participants</p>
Author(s) -
Haiyan Li,
Zhenhua Yang,
Shuang Zhang,
Lin Xu,
Yudong Wei,
Jun Jiang,
Luzelena Caro,
HwaPing Feng,
Jacqueline B. McCrea,
Meng Li,
Shuang Xie,
Jiangdian Wang,
Xu Zhao,
Shengmei Mu
Publication year - 2020
Publication title -
clinical pharmacology
Language(s) - English
Resource type - Journals
ISSN - 1179-1438
DOI - 10.2147/cpaa.s224662
Subject(s) - medicine , pharmacokinetics , tolerability , fixed dose combination , pharmacology , adverse effect
The burden of hepatitis C virus infection is particularly high in Asian countries, and new treatments are urgently needed. The purpose of this study was to characterize the pharmacokinetics (PK) and safety of the fixed-dose combination tablet of elbasvir/grazoprevir in healthy Chinese participants.