Open AccessAutophagy Induced by BCL2-Related ceRNA Network Participates in the Occurrence of COPD
Author(s) -
Zhuang-E Shi,
Mengyu Zhang,
Jian-Yu Liu,
Wendi Zhang,
Di Hu,
Qingxiang Wang,
Xiu-Li Ji,
Yuanyuan Jiang,
Yi-Qing Qu
Publication year - 2022
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s347733
Subject(s) - autophagy , competing endogenous rna , microrna , copd , biology , gene , in silico , becn1 , computational biology , bioinformatics , medicine , rna , genetics , long non coding rna , apoptosis
Chronic obstructive pulmonary disease (COPD) is a predominant cause of mortality worldwide. Autophagy, which depends on a lysosomal degradation pathway, plays an essential role in the occurrence of COPD. The aim of our study was to identify the potential function of autophagy and construct a BCL2-related competing endogenous RNA (ceRNA) network that induces autophagy in COPD.